Coleus forskohli is a member of the Lamiaceae family that was discovered in India at lower elevations. The root is used of many medicinal purposes such as heart and lung diseases, weight loss, insomnia, glaucoma, depression and allergies.
Forskolin is a chemical found in the coleus herb that activates the enzyme adenylate cyclase. Andenylate cyclase compound instigates many critical events and processes within all the cells of the human body. Adenylate cyclase and the chemicals it activates are responsible for executing a number of important hormonal processes.
Studies done in a lab show that coleus stimulates fat metabolism. Researchers have found that many obese/overweight people have lower than normal Cyclic AMP production. Because of these considerations, coleus may, in theory, be a weight loss instrument. In a recent study, overweight women took 25 mg of coleus (250 mg capsules of 10% standardized forskolin extract) twice daily for eight weeks. At the end of the eight-week trial, the participants lost a mean of ten pounds, and reduced their percentage of body fat by nearly 8%.
A few studies in humans have shown evidence that direct of a special application of forskolin to the eyes can lower eye pressure and reduce the risk of glaucoma. Keep in mind this is a special application process and application of the whole herb to the eyes has not been studied and is not recommended by any medical professionals.
Forskolin may also assist in the dilation of blood vessels and possibly improving the power at which the heart pumps blood throughout the body. With dilation of blood vessels by forskolin may also help to lower blood pressure and improve heart function.
By raising cAMP, forskolin is responsible for:
Increased fat metabolism (breakdown of fat)
Increased force of contraction of heart muscle.
Increased thyroid function.
Increased insulin secretion.
Relaxation of the arteries and other smooth muscle.